منابع مشابه
chronic pain in chronic heart failure: a review article
heart failure (hf) is one of the main causes of death and disability in the world. the prevalence of hf in developed countries is between 1% and 2% of the adult population and approximately between 6% and 10% in the elderly, giving rise to high costs of care and treatment. indeed, in the united states, the direct and indirect costs exceeded 23 billion dollars in 2002. hf is typically character...
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Nowadays, the inhibitors of the phosphodiesterase enzyme type 5 (PDE5), thanks to a sustained relaxant activity on smooth muscles of the corpus cavernosum, are a widely used remedy for erectile dysfunction in man. This class of compounds was originally developed for the treatment of angina pectoris, based on the ability of oversignaling the pathway originated from nitric oxide (NO) and pursued ...
متن کاملMetoprolol: a review of its use in chronic heart failure.
UNLABELLED Metoprolol, a relatively selective beta1-blocker, is devoid of intrinsic sympathomimetic activity and possesses weak membrane stabilising activity. The drug has an established role in the management of essential hypertension and angina pectoris, and more recently, in patients with chronic heart failure. The effects of metoprolol controlled-release/extended-release (CR/XL) in patients...
متن کاملClinical use of phosphodiesterase-5 inhibitors in chronic heart failure.
Nowadays, the inhibitors of the phosphodiesterase enzyme type 5 (PDE5), thanks to a sustained relaxant activity on smooth muscles of the corpus cavernosum, are a widely used remedy for erectile dysfunction in man. This class of compounds was originally developed for the treatment of angina pectoris, based on the ability of oversignaling the pathway originated from nitric oxide (NO) and pursued ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2005
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2004.10.082